Keeping up-to-date
Drug Safety Updates
Drug Safety Updates contain information and clinical advice from the MHRA and the Commission on Human Medicines (CHM), its independent advisor, about the safe use of medicines. Drug Safety Updates are intended for all healthcare professionals who work in the UK – doctors, pharmacists, nurses, dentists, allied healthcare professionals and coroners. They replaced Current Problems in Pharmacovigilance in July 2007. Access current and previous publications and search for details on individual drugs and reactions via: Drug Safety Update
‘Dear Healthcare Professional’ Letters
‘Dear Healthcare Professional’ Letters are circulations designed to communicate important new information about a marketed product to the healthcare professionals who will be involved in its use. They are generally produced by the pharmaceutical industry to supply details of important safety warnings and messages for medicines including letters sent to help professionals in the event of major/urgent drug safety issues.
You can find a list of recent and archived ‘Dear Healthcare Professional’ Letters here.
Interactive Drug Analysis Profiles (iDAPs)
iDAPs contain complete listings of all suspected adverse drug reactions or side effects, which have been reported by healthcare professionals and patients to the MHRA, via the Yellow Card Scheme.
Each iDAP lists all of the reactions reported by health professionals and patients for a particular medicine. Medicines are listed alphabetically by the name of the active ingredient, not the brand name.
The interactivity of the profiles allows users to manipulate the data to better understand the types of reactions reported, and who they were reported by. A list of iDAPs can be found via: Interactive Drug Analysis Profiles
If there are no iDAPs available, e.g. for vaccines, you should send an email request to the MHRA Pharmacovigilance mailbox: pharmacovigilanceservice@mhra.gsi.gov.uk
They aim to turn around all enquiries within 7 to 10 working days.
Product-Specific Information & Advice
Below you will find a link to product-specific information produced by the MHRA as guidance for healthcare professionals on the management and safe use of individual medicines and medical devices, including hormone replacement therapies, oral contraceptives, breast implants and vaccines.